Endocrine Abstracts

Objective: We aimed to examine sexual dysfunction frequency and relationship between sexual dysfunction and androgen level in polycystic ovary syndrome.Patients and methods: Twenty-five PCOS patients were recruited from the outpatient clinics of the Division of Endocrinology in the Department of Internal Medicine and outpatient clinics of the Department Obstetrics and Gynecology at the Cerrahpasa Medical Faculty. Twenty-five healthy volunteer age and sex...

Background: Currently, there is no satisfying treatment option other than gross total or subtotal resection in combination with adjuvant radiotherapy for the treatment of craniopharyngiomas. However, recurrence could occur in a substantial proportion of craniopharyngiomas despite gross total resection and radiotherapy. Human epidermal growth factor receptor 2 (HER-2/ErbB2) overexpression was determined in various human carcinomas and is associated with aggressive clinical beha...

Introduction: The treatment of choice in Cushing’s disease (CD) is transsphenoidal adenomectomy. However, the long term recurrence rate of the CD after transsphenoidal surgery in Turkish patients has not been determined so far.Purpose: We aimed to determine the long term recurrence rates of CD in Turkish patients after transsphenoidal surgery.Methods: The computer records of the 23 patients, operated for CD in our center durin...

Background: With the increasing use of USG, MRI and CT, adrenal lesions are frequently found in the daily practice. These lesions may be primary or secondary in origin. However, it is important to resolve whether these lesions are benign or malignant.Purpose: The aim of this case detection study was to compare FDG-PET CT with MRI in differentiating benign from malignant adrenal mass lesions.Patients: All patients were admitted to o...

Background: Currently, multiple treatment options are available for the treatment of acromegaly. However, cure is obtained only in 50% of patients with macroadenomas after surgery. Persistent tumor enlargement occur in 2.2% of the patients treated with somatostatin analogs and in 1.6–2.9% of the patients treated with pegvisomant. The nuclear antigen Ki-67 is related to growth potential and is also a major prognostic indicator for pituitary adenomas. Studies demonstrated t...